Science Digest Newsletter January 2024
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JANUARY 2024

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Cover_January 2024_1_SD

Acetylcholinesterase inhibition in rats and humans following acute fenitrothion exposure predicted by physiologically based kinetic modeling-facilitated quantitative in vitro to in vivo extrapolation

 

Journal
Environmental Science & Technology,
Vol. 57(49) (2023), 20521–2053.

 

Authors
Jiaqi Chen, Shensheng Zhao, Sebastiaan Wesseling, Nynke Kramer, Ivonne Rietjens, Hans Bouwmeester

 

Work package
5,6

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Cover_January 2024_2_SD

Ecotoxicological evaluation of bisphenol A and alternatives:
A comprehensive in silico modelling approach

 

Journal
Journal of Xenobiotics, Vol. 13(4) (2023), 719-739.

 

Authors
Liadys Mora Lagares, Marjan Vračko

 

Work package
5

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Cover_January 2024_3_SD

Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration

 

Journal
Environment International, Vol. 180 (2023), 108229

 

Authors
Anna-Katharina Ückert, Sina Rütschlin, Simon Gutbier, Nathalie Christine Wörz, Mahfuzur R. Miah, Airton C. Martins, Isa Hauer, Anna-Katharina Holzer, Birthe Meyburg, Ann-Kathrin Mix, Christof Hauck, Michael Aschner, Thomas Böttcher, Marcel Leist

 

Work package
5

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Cover_January 2024_4_SD

A data-derived reference mixture representative of European wastewater treatment plant effluents to complement mixture assessment

 

Journal

Environment International, Vol. 179 (2023), 108155

 

Authors
Liza-Marie Beckers, Rolf Altenburger, Werner Brack, Beate I. Escher, Jörg Hackermüller, Enken Hassold, Gianina Illing, Martin Krauss, Janet Krüger, Paul Michaelis, Andreas Schüttler, Sarah Stevens, Wibke Busch

 

Work package
6

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Cover_January 2024_5_SD

Deoxynivalenol increases pro-inflammatory cytokine secretion and reduces primary bile acid transport in an inflamed intestinal in vitro co-culture model

 

Journal
Food Research International, Vol. 173
(Part 1) (2023), 108297

 

Authors
Jingxuan Wang, Wouter Bakker, Laura de Haan, Hans Bouwmeester

 

Work package
5,6

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Cover_January 2024_6_SD

G × E interactions as a basis for toxicological uncertainty

 

Journal

Archives of Toxicology, Vol. 97(7) (2023), 2035–2049.

 

Authors
Ilinca Suciu, David Pamies, Roberta Peruzzo, Petra H. Wirtz, Lena Smirnova, Giorgia Pallocca, Christof Hauck, Mark T. D. Cronin, Jan G. Hengstler, Thomas Brunner, Thomas Hartung, Ivano Amelio, Marcel Leist

 

Work package
6

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More info on eu-parc.eu

List of work packages (WPs)

WP 1 Partnership management and coordination
WP 2 A common science-policy-agenda
WP 3 Synergies, collaborations and awareness
WP 4 Monitoring and exposure
WP5 Hazard assessment

WP 6 Innovation in regulatory risk assessment
WP 7 FAIR data
WP 8 Concepts and toolboxes
WP 9 Building infrastructural and human capacities

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