Towards prospective identification of respiratory sensitizers: effects of piperazine, chloramine-T, and toluene-diisocyanate in an air-liquid interface model comprising human bronchial epithelial cells

Journal
Archives of Toxicology, (2025)

Authors
Evert Duistermaat, Véronique M.P. de Bruijn, Jolanda P. Vermeulen, Eric R. Gremmer, Rob J. Vandebriel

Work package
5

Journal
International Journal of Molecular Sciences, Vol. 26 (4) (2025), 1674.

Authors
Niki Tagkalidou, Marija Stevanović, Irene Romero-Alfano, Gustavo Axel Elizalde-Velázquez, Selene Elizabeth Herrera-Vázquez, Eva Prats, Cristian Gómez-Canela, Leobardo Manuel Gómez-Oliván, Demetrio Raldúa

Work package
5

Automated curation of spatial metadata in environmental monitoring data

Journal
Ecological Informatics, Vol. 86 (2025), 103038.

Authors
Ilhan Mutlu, Jörg Hackermüller, Jana Schor

Work package
7

A comprehensive library of lifetime physiological equations for PBK models: Enhancing dietary exposure modeling with mercury as a case study

Journal
Environmental Research, Vol. 265 (2025), 120393.

Authors
Thomas Gastellu, Achilleas Karakoltzidis, Aude Ratier, Marie Bellouard, Jean-Claude Alvarez, Bruno Le Bizec, Gilles Rivière, Spyros Karakitsios, Dimosthenis A. Sarigiannis, Carolina Vogs

Work package
6

A preliminary estimate of the environmental burden of disease associated with exposure to pyrethroid insecticides and ADHD in Europe based on human biomonitoring

Journal
Environmental Health, Vol. 23 (2024), 91.

Authors
Anthony Purece, Sofie Theresa Thomsen, Dietrich Plass, Anastasia Spyropoulou, Kyriaki Machera, Philippe Palmont, Amélie Crépet, Rafiqa Benchrih, Brecht Devleesschauwer, Nina Wieland, Paul Scheepers, Deepika Deepika, Vikas Kumar, Gerardo Sanchez, Jos Bessems, Dario Piselli, Jurgen Buekers

Work package
6

Progress, applications, and challenges in high-throughput effect-directed analysis for toxicity driver identification - Is it time for HT-EDA?

Journal
Analytical and Bioanalytical Chemistry, Vol. 417 (2025), 451-472.

Authors
Iker Alvarez-Mora, Katarzyna Arturi, Frederic Béen, Sebastian Buchinger, Abd El Rahman El Mais, Christine Gallampois, Meike Hahn, Juliane Hollender, Corine Houtman, Sarah Johann, Martin Krauss, Marja Lamoree, Maria Margalef, Riccardo Massei, Werner Brack, Melis Muz

Work package
4

Chemical respiratory sensitization - Current status of mechanistic understanding, knowledge gaps and possible identification methods of sensitizers

Journal
Frontiers in Toxicology, Vol. 6 (2024), 1331803.

Authors
Rita Hargitai, Lucia Parráková, Tünde Szatmári, Pablo Monfort-Lanzas, Valentina Galbiati, Karine Audouze, Florence Jornod, Yvonne C M Staal, Sabina Burla, Aline Chary, Arno C Gutleb, Katalin Lumniczky, Rob J Vandebriel, Johanna M Gostner

Work package
5

AOPWIKI-EXPLORER: An interactive graph-based query engine leveraging large language models

Journal
Computational Toxicology, Vol. 30 (2024), 100308.

Authors
Saurav Kumar, Deepika Deepika, Karin Slater, Vikas Kumar

Work package
7

Revealing the cascade of pesticide effects from gene to community

Journal
Science of the Total Environment, Vol. 917 (2024), 170472.

Authors
Ayesha Siddique, Naeem Shahid, Matthias Liess

Work package
6

Curated mode-of-action data and effect concentrations for chemicals relevant for the aquatic environment

Journal
Scientific Data, Vol. 11 (2024), 60.

Authors
Lena Kramer, Tobias Schulze, Nils Klüver, Rolf Altenburger, Jörg Hackermüller, Martin Krauss, Wibke Busch

Work package
7